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RESEARCH HIGHLIGHTS

Dr. Khalsa and the ARPF were the first to recommend an integrative or holistic program for building a healthier, stronger brain, thus slowing the development of cognitive decline. Since then, the ARPF’s 4 Pillars of Alzheimer’s Prevention have been incorporated by other Alzheimer’s groups and this concept is now considered mainstream. Indeed, the ARPF is now partnering with the FINGER study (Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability), the largest study in history on Alzheimer's prevention.

Studies

Reversal of Memory Loss

Results of this study, published in the Journal of Alzheimer’s Disease, revealed for the first time, that a simple, 12 minute yoga meditation improved memory in people with memory loss
Meditation Effects on Cognitive Function and Cerebral Blood Flow in Subjects with Memory Loss: A Preliminary Study.
Journal of Alzheimer’s Disease

Improved Brain Blood Flow and Activation of Important Areas Associated with Alzheimer’s Prevention

In our first study, we utilized SPECT scans and showed that only 11 minutes of this yoga meditation dramatically improved brain health. This study also revealed activation of an important anatomical area that declines with memory loss.
Cerebral Blood Flow Changes During Chanting Meditation.
Nuclear Medicine Communications

Improvement in Mood and Reduced Stress in People with Memory Loss

This paper showed that our simple 12 minute yoga meditation program in people with memory loss was associated with positive changes in mood, anxiety, and improved brain blood flow.
Effects of an 8 Week Meditation Program on Mood and Anxiety in Patients with Memory Loss.
The Journal of Alternative and Complementary Medicine

The Anti-Aging Effect of Meditation

This paper determined that people who meditate have a younger, healthier-looking brain. They also have more brain blood flow at rest.
Cerebral Blood Flow Differences Between Long-Term Meditators and non-Meditators.
Journal of Consciousness and Cognition

Different Meditations Have Different Effects on the Brain

For the first-time ever, we showed that different meditation techniques create differences in brain blood flow and activation of distinct, important areas in the brain. These changes correlate with the depth of meditation, spiritual connectedness, and stress reduction.
Cerebral Blood Flow Changes Associated with Different Meditation Practices and Perceived Depth of Meditation.
Psychiatry Research: Neuroimaging

Yoga Meditation Associate with Better Mental Health

This study was done in highly stressed, family dementia caregivers. It revealed a high level of improvement in mental health and depression in those who practiced the 12 minute yoga meditation called Kirtan Kriya daily for 8 weeks.
A Pilot Study of Yoga Meditation for Family Caregivers with Depressive Symptoms: Effects on Mental Health, Cognition, and Telomerase Activity.
International Journal of Geriatric Psychiatry

Yoga Meditation Associated with Better Memory Function

In the same study, it was shown that highly stressed family caregivers of dementia patients who practiced this particular yoga meditation scored higher on memory tests than the control group.
A Pilot Study of Yoga Meditation for Family Caregivers with Depressive Symptoms: Effects on Mental Health, Cognitiion, and Telomerase Activity.
International Journal of Geriatric Psychiatry

Increase in telomerase, the enzyme that maintains telomere length (DNA health)

Results of this study, published in the International Journal of Geriatric Psychiatry, showed the largest increase ever in the enzyme telomerase, which is responsible for maintaining telomere length. Telomeres are the end of chromosomes that influence our longevity, health, and cognitive function.
A Pilot Study of Yoga Meditation for Family Caregivers with Depressive Symptoms: Effects on Mental Health, Cognition, and Telomerase Activity.
International Journal of Geriatric Psychiatry

Brain Function Improved

Yoga meditation in distressed caregivers resulted in improved brain function in significant areas.
A Pilot Study of the Effects of Meditation on Regional Brain Metabolism in Distressed Dementia Caregivers.
Aging Health

Yogic Meditation Improves Genetic Health

In this study, it was seen that the 12 minutes yoga meditation, practiced daily, caused good genes to be ‘up regulated’ and bad genes to be ‘down regulated.’
Yoga Meditation Reverses NF-kB and IRF-related Transcriptome Dynamics in Leukocytes of Family Dementia Caregivers in a Randomized Controlled Trial.
Psychoneuroendocrinology

Yogic Meditation Improves Genetic Health

In the same study as above, inflammatory levels in the body (pro-inflammatory nuclear factors NF-kB) was decreased while Interferon response factors (IRF’s) were increased. This demonstrates a reversal of the negative effects of stress.
Yoga Meditation Reverses NF-kB and IRF-related Transcriptome Dynamics in Leukocytes of Family Dementia Caregivers in a Randomized Controlled Trial.
Psychoneuroendocrinology

For a list of journal articles published on the Alzheimer's Research and Prevention Foundation's research, see our Journal Articles page.